Struggling with chronic anxiety can take a serious toll—draining your energy, disrupting focus and sleep, and diminishing your overall well-being. At Hydrate Medical in Cary, NC, our NAD+ Therapy offers a medically supervised, provider-led approach to help support your body’s natural stress response and neurochemical balance.
We offer both NAD+ IV infusions and convenient subcutaneous (SubQ) injections as part of a supportive wellness plan. While not a substitute for professional mental health treatment, NAD+ therapy can serve as a powerful adjunct—promoting cellular repair and metabolic function to help you feel more balanced and resilient.
Important note: NAD+ therapy is not a recognized treatment for diagnosed anxiety disorders and should not replace care from a licensed mental health professional. If you’re in a crisis, call or text 988 for immediate support.
NAD+ is essential for energy production within cells, supports mitochondrial function, and plays a role in the creation of neurotransmitters—all of which are involved in mood and stress regulation. Some studies suggest that low NAD+ levels may be linked to anxiety symptoms, especially in cases involving chronic fatigue or long-term stress.
A study by Alegre and colleagues in 2010 explored oral NADH supplements in patients with chronic fatigue syndrome. The double-blind, placebo-controlled trial showed a statistically significant reduction in anxiety scores for the NADH group (p < 0.05). While the participants had chronic fatigue, the observed decrease in anxiety suggests a potential benefit for those experiencing similar symptoms.
A 2024 systematic review published in the American Journal of Physiology examined multiple randomized clinical trials. It found that NADH and NAD+ precursor supplements were generally well tolerated and associated with lower anxiety symptoms and better quality of life outcomes.
Important context: Most of the current research focuses on individuals with chronic fatigue or studies where anxiety was a secondary outcome. There is a lack of large, targeted trials specifically assessing NAD+ therapy for anxiety disorders. While early findings are encouraging, more research is needed to fully understand the potential role of NAD+ in managing anxiety.
Comprehensive cellular support delivered in a quiet, comfortable setting designed to promote relaxation during treatment.
A quicker option for maintenance or ongoing support.
Brief in-office visits Can be self-administered with guidance from a provider Often used as follow-up to IV treatment or as a standalone option Pricing is available during consultation
Relaxing, private lounge setting Infusion rate adjusted based on your comfort Continuous monitoring by experienced nursing staff Optional comforts like streaming, refreshments, or a quiet environment
Most individuals tolerate treatment well, but some may experience nausea, flushing, headache, or a temporary increase in anxiety. These symptoms are often manageable by adjusting the infusion rate.
NAD+ therapy is not a cure for anxiety. Anxiety is a complex condition influenced by brain chemistry, life experiences, trauma, and genetics.
If you’re experiencing a mental health crisis, call or text 988 for the Suicide & Crisis Lifeline. NAD+ therapy is not a crisis intervention.
Hydrate Medical® provides wellness services under clinical oversight. Content is educational and not a substitute for personalized medical or mental health advice. Individual results vary. NAD+ therapy is not FDA-approved for treating anxiety disorders and should not replace professional mental health care.
NAD+ Treatments